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"The Dallas County Medical Examiner has confirmed 10 fatalities and no survivors," a spokeswoman for the town of Addison, Texas told AFP.
The National Transportation Safety Board tweeted that it had dispatched a team to Addison to investigate the crash of a King Air 350 -- a twin-engine turboprop passenger plane.
It did not provide further details on the crash or its cause.
Video broadcast by US media showed a massive column of black smoke pouring out of a building at the airport, as firefighters directed streams of water toward the blaze.
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CNN reported that the aircraft was a private plane and that it crashed into a hanger at a local airport.
CBS News quoted sources as saying the aircraft lost an engine on takeoff and veered into the hanger.